Kicking off at 7pm in Leyland, David Lee's side will be looking to build off the back of their victory against Sheffield United last time out.
They are unbeaten on their own soil meanwhile, having won five out of six games in front of their own supporters so far this term.
Their form in general has seen them win eight, draw one and lose three matches to leave them sitting top of the Professional Development League North Section.
Sheffield United however have won six, drawn three and lost three games and sit fifth with 21 points from 12 outings.
Last time out, they won 2-1 over Birmingham City in a 2-1 away victory.