The U23s currently sit third in the North Section of the Professional Development League after 13 games, having won eight, drawn two and lost three of their outings so far.
Coming off the back of a 1-1 draw against Sheffield United, the boys will be looking to go one further and make their game in hand count over leaders Leeds United.
When looking at the Railwaymen's team meanwhile, they sit sixth in the North Section of the Professional Development League.
With 21 points taken from a possible 39, the Alex come into the game off the back of a 3-2 win over Hull City on November 19.
Admission is free for all at the Alexandra Stadium, with a report of the match on bwfc.co.uk shortly after full time.