Depends what kind of food you want.
For fine (ish) dining using some fantastic locally sourced produce - Nicks on chequerbent (used to be Chequers) is fantastic, great service with well trained and attentive staff who know the products they sell well and a regularly changing menu. Highly recommended.
For Chinese you actually cannot beat the china rooms in westhoughton. Seriously.
Indian - India gate is pretty good, was better when it was in Tottington though.
For a 'normal' nice weekend feed, Retreat on Chorley old road is great, especially in summer as you can have mojito's on the patio pre-meal.
Olives in Turton is also pretty good for this.
I agree with Nat, the reebok IS actually good, Ate in Reflections a few times, however not since the new team took over so cant comment at present.
I know its a chain, but I rate Chiquito's as well.