Coming off the back of an empathic 3-2 victory with ten men against Nottingham Forest, the boys will be looking to build on this against the Owls.
The U23s currently sit fifth in the North Section of the Professional Development League after 17 games, having won nine, drawn two and lost six of their outings so far.
When looking at the Wednesday team meanwhile, they sit seventh in the North Section of the Professional Development League.
With 22 points taken from a possible 51, Neil Thompson's men come into the game off the back of a 1-0 victory against Burnley U23s on January 7.
A report of the match will be on bwfc.co.uk following the final result.